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Useful in probe design for hybridization assays
TBDMS deprotection can be achieved using fluoride reagents (e
3 (2008): 301-305
color: #3361ac
DMT-2'-O-TBDMS-U-CE Phosphoramidite Application_Diagnostics Useful in probe design forDMT 2' O TBDMS U CE Phosphoramidite is a protected ribonucleoside building block used for solid phase RNA oligonucleotide synthesis. It contains a 5' dimethoxytrityl (DMT) protecting group for 5' hydroxyl protection, a 2' O tert butyldimethylsilyl (TBDMS) protecting group for 2' hydroxyl protection, a cyanoethyl (CE) protecting group on phosphite, and a uracil. TBDMS offers excellent stability for protecting 2' hydroxyl of ribonucleosides during acid
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