such as Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD)
CNOT1 itself does not possess catalytic activity but is essential for maintaining the integrity of the CCR4-NOT complex and binding to other subunits and RNA-binding proteins
Its specific function is to retain unfolded or unassembled N-linked glycoproteins in the ER
Species Human Antigen IL-7R alpha/CD127 Synonyms Interleukin-7 receptor subunit alpha,Interleukin 7 Receptor Isoform H5-6,CDw127,IL-7R subunit alpha,IL-7RA,IL-7 receptor subunit alpha,CD127 Antigen,IL-7R-Alpha,Interleukin 7 Receptor Alpha Chain,CD127,IL7RA,ILRA,Interleukin-7 Receptor alpha Subunit Accession P16871 Amino Acid Sequence Glu21-Asp239
IL-1 beta Recombinant Rabbit mAb (S-3173) Size:100μl such as Amyotrophic Lateral SclerosisProduct Specification Host Rabbit Antigen IL 1 beta Synonyms Interleukin 1 beta; Catabolin; IL1F2; IL1B Location Cytoplasm, Secreted, Lysosome Accession P01584 Clone Number S 3173 Antibody Type Recombinant mAb Isotype IgG Application WB, ICC Reactivity Hu, Ms Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months